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Search Results for " aldehyde oxidase "

Targets Recommended: Others

抑制剂 & 化合物

天然产物

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T50059	6-ethenylquinoline	Others	Others
	6-ethenylquinoline 是一种结构独特的芳香杂环化合物，是生产其他芳香族化合物的重要中间体，并被用作合成各种药物的起始材料，包括抗真菌剂、抗寄生虫剂和抗病毒剂。它已被证明是多种参与药物代谢的酶的抑制剂，包括细胞色素P450、醛氧化酶和黄嘌呤氧化酶等。
T22622	Carbazeran citrate	Others	Others
	aldehyde oxidase (AO) substrate
T78358	Choline oxidase
	Choline oxidase 通过催化胆碱氧化成甜菜碱醛，在甘氨酸甜菜碱生物合成中扮演关键角色，汲取其作为渗透剂的功能。此酶在促进甜菜碱生产方面展现出潜力。
T37533	DOPAL
	DOPAL is an aldehyde product of the oxidative deamination of dopamine by monoamine oxidase.[1] It can be further oxidized to 3,4-dihydroxyphenylacetic acid (DOPAC) by aldehyde dehydrogenase (ALDH) and, to a lesser extent reduced to 3,4-dihydroxyphenyl ethanol (DOPET). DOPAL is toxic to neurons.[2],[3] It can also oligomerize and precipitate α-synuclein, an event associated with Parkinson's disease.[2] Mice lacking cytosolic and mitochondrial forms of ALDH display increased levels of DOPAL as wel...
T23210	Quinacrine (dihydrochloride hydrate) Quinacrine (hydrochloride hydrate) (83-89-6 free base)	Others	Others
	Quinacrine is a compound that is commonly used as an anti-protozoal agent. It inhibits voltage-dependent sodium channels (IC50: 3.3 μM） and suppresses aldehyde oxidase (IC50: 3.3 μM). Quinacrine prevents misfolding of prion protein (EC50: 0.3 μM). As an e
T63026	JAK-IN-19
	JAK-IN-19 是一种 JAK 的有效抑制剂，对 PBMC IFNγ 和 HLF Eotaxin 的 pIC50 值分别为 7.2 和 7.7。JAK-IN-19 能够减轻被醛氧化酶 (Aldehyde Oxidase, AO) 代谢，进而保持在肺内的良好保留特性，对 VEGFR2 选择性较低（对 VEGFR2 和 Aurora B 的 pIC50 值分别为 7.0 和 5.8）。

化合物

Quinacrine (dihydrochloride hydrate)

Cat.No: T23210

Synonym: Quinacrine (hydrochloride hydrate) (83-89-6 free base)

Cat. No.	Product Name	Target	Signaling Pathways
T3740	Isovanillin 3-羟基-4-甲氧基苯甲醛,3-Hydroxy-p-anisaldehyde,3-Hydroxy-4-methoxybenzaldehyde,5-Formylguaiacol	Others	Others
	Isovanillin (5-Formylguaiacol) 是一种醛氧化酶抑制剂，具有解痉挛和止泻活性。

天然产物

Isovanillin

Cat.No: T3740

Synonym: 3-羟基-4-甲氧基苯甲醛,3-Hydroxy-p-anisaldehyde,3-Hydroxy-4-methoxybenzaldehyde,5-Formylguaiacol

Target: Others

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPH-00913	AOX1 Protein, Human, Recombinant (His) Aldehyde oxidase,AO,Azaheterocycle hydroxy...	Human	E. coli
	AOX1 Protein, Human, Recombinant (His) is expressed in E. coli.
TMPJ-00380	AOC3 Protein, Human, Recombinant (His) Membrane primary amine oxidase,HPAO,VAP-1,Semicarba...	Human	HEK293 Cells
	Vascular adhesion protein-1(VAP-1) is a copper amine oxidase with a topaquinone cofactor.VAP-1 is a type II integral membrane protein, but a soluble form of the enzyme is present in human serum, and its level increases in diabetes and some inflammatory liver diseases. VAP-1 catalyzes the oxidative deamination of small primary amines such as methylamine, benzylamine, and aminoacetone in a reaction that produces an aldehyde, ammonia, and H2O2. VAP-1 vascular expression is regulated at sites of inf...